Journal: The BMJ
Article Title: Association of computed tomography screening with lung cancer stage shift and survival in the United States: quasi-experimental study
doi: 10.1136/bmj-2021-069008
Figure Lengend Snippet: Trends from 2010 to 2018 in percentage of stage I non-small cell lung cancer diagnosed (top) and in median all cause survival (bottom) among patients aged 55-79 in Surveillance Epidemiology End Results Program database living in high screening (US states where lung cancer screening rate is above national average lung cancer screening rate in 2018) and low screening (US states where lung cancer screening rate is below national average lung cancer screening rate in 2018) states. Each consecutive annual interval is represented as a point value. Vertical dotted line represents date when United States Preventive Services Task Force (USPSTF) first recommended low dose computed tomography (LDCT) lung cancer screening. Annual percentage changes were as follows. Low screen, percentage diagnosed 2010-12: 1.0%, P=0.40; 2012-18: 3.7%, P<0.001. High screen, percentage diagnosed 2010-13: 0.9%, P=0.41; 2013-18: 5.4%, P<0.001. Low screen, median survival 2010-17: 5.9%, P<0.001. High screen, median survival 2010-14: 2.2%, P=0.39; 2014-17: 13.4%, P=0.04. “Raw” denotes actual percentage of patients with stage I disease at diagnosis and median all cause survival of patients each year. “Model” denotes results of joinpoint regression modeling. An interactive version of this graphic is available at https://public.flourish.studio/visualisation/8876566/
Article Snippet: We used Joinpoint Software Version 4.9.0.0 and Stata/MMP Version 17.0 for PC for statistical analyses.
Techniques: Computed Tomography, Biomarker Discovery